TPDB

3D PDB MODEL

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TPDB ID TPDB41697

Activity

Anticancer

Activity_category_statistics

Cancer-related peptides

Database_Source

dbACP

Sequence_Type

standard

Has_Modification No

Description A 281-aa standard natural anticancer peptide sequence curated from dbACP, with an available 3D structural model.

Sequence

MEANTRSTGRLPAAFLTPGSSSFMDFLGEHQPEILPGNRQLPPVQGAIEAPHGTTIVAVTFPGGVVLAGDRRATMGNMIAQRDVEKVFPADEYSAVGIAGTAGLAVEMVKLFQLELEHFEKVEGAQLSLEGKANRLSTMIRSNLGMAMQGLAVVPLFAGYDVDRGRGRIFSYDVTGGRSEELNFATTGSGSIFARGAMKKLFHDELTEEQATTLVVQALYDAADDDSATGGPDVARRIYPIITVITEDGFRRLGEDECSALARSVLERRLEQPDGPRAALL

FASTA

>TPDB41697|Anticancer|length=281
MEANTRSTGRLPAAFLTPGSSSFMDFLGEHQPEILPGNRQLPPVQGAIEAPHGTTIVAVTFPGGVVLAGDRRATMGNMIAQRDVEKVFPADEYSAVGIAGTAGLAVEMVKLFQLELEHFEKVEGAQLSLEGKANRLSTMIRSNLGMAMQGLAVVPLFAGYDVDRGRGRIFSYDVTGGRSEELNFATTGSGSIFARGAMKKLFHDELTEEQATTLVVQALYDAADDDSATGGPDVARRIYPIITVITEDGFRRLGEDECSALARSVLERRLEQPDGPRAALL

Formula C1321H2110N374O412S10

Absent Amino Acids W

Common Amino Acids A

Mass 30144.14

PI 4.74

Basic Residues 31

Acidic Residues 38

Hydrophobic Residues 118

Net Charge -11

Boman Index 65.72

Hydrophobicity -0.110

Aliphatic Index 86.16

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 7450

Absorbance 280nm 24.71

Polar Residues 55

number

32

A

21

R

6

N

16

D

1

C

22

E

10

Q

30

G

4

H

12

I

27

L

6

K

9

M

13

F

14

P

15

S

18

T

0

W

5

Y

20

V

Amino Acid Distribution

A: 32 R: 21 N: 6 D: 16 C: 1 E: 22 Q: 10 G: 30 H: 4 I: 12 L: 27 K: 6 M: 9 F: 13 P: 14 S: 15 T: 18 W: 0 Y: 5 V: 20

Length

281

Formula

C1321H2110N374O412S10

Mass

30144.14

PI

4.74

Net Charge

-11

Boman Index

65.72

Hydrophobicity

-0.110

Evidence 1 Activity

Source & Reference

Database Source dbACP