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Peptide record

TPDB41689

MP12 Anticancer standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB41689
MP12
Anticancer
Cancer-related peptides
CancerPPD 2.0 dbACP
standard
No
A 12-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0 and dbACP, with an available 3D structural model.
Sequence
MDNHVCIPLCPP
Physicochemical Analysis
C57H91N15O16S3
AREQGKFSTWY
P
1338.62
4.94
1
1
4
-1
2.45
0.367
89.17
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
9.34
3
Residue Composition
number
0
A
0
R
1
N
1
D
2
C
0
E
0
Q
0
G
1
H
1
I
1
L
0
K
1
M
0
F
3
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 1 C: 2 E: 0 Q: 0 G: 0 H: 1 I: 1 L: 1 K: 0 M: 1 F: 0 P: 3 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
12
C57H91N15O16S3
1338.62
4.94
-1
2.45
0.367
Free
L
Linear
Free
Antiproliferative
Aphanomyces invadans
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
IC50 = 24.7 ± 0.34 µM
Anticancer
24.7

Target

Larynx Cancer
Hep-2
Larynx

Assay & Model

MTT assay
Not Available

Source & Reference

CancerPPD 2.0 dbACP
CancerPPD2
2022

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.