TPDB

3D PDB MODEL

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TPDB ID TPDB41688

Activity

Anticancer

Activity_category_statistics

Cancer-related peptides

Database_Source

dbACP

Sequence_Type

standard

Has_Modification No

Description A 305-aa standard natural anticancer peptide sequence curated from dbACP, with an available 3D structural model.

Sequence

MDLGTSEAATLEQPPGPDGTNPHERPRSLWTDAWHDLRRNPVFIISALVILFLVVISLWPSLIASGSPLKCDLAKAQEGSQPGHPFGFNGQGCDVYTRTVYGARTSVAVGILATLGVALLGSVLGGLAGFFGGAGDAVLSRITDVFFAIPVVLGGLVLLSVITSNTVWPVIGFIVLLGWPQISRIARGSVITAKQNDYVQAARALGASNSRLLLRHIAPNAIAPVIVVATIALGTYISLEATLSFLGVGLKPPSVSWGIDISAAAPYVRNAPHALLWPSGALAVTVLAFIMLGDAVRDALDPKLR

FASTA

>TPDB41688|Anticancer|length=305
MDLGTSEAATLEQPPGPDGTNPHERPRSLWTDAWHDLRRNPVFIISALVILFLVVISLWPSLIASGSPLKCDLAKAQEGSQPGHPFGFNGQGCDVYTRTVYGARTSVAVGILATLGVALLGSVLGGLAGFFGGAGDAVLSRITDVFFAIPVVLGGLVLLSVITSNTVWPVIGFIVLLGWPQISRIARGSVITAKQNDYVQAARALGASNSRLLLRHIAPNAIAPVIVVATIALGTYISLEATLSFLGVGLKPPSVSWGIDISAAAPYVRNAPHALLWPSGALAVTVLAFIMLGDAVRDALDPKLR

Formula C1464H2327N387O401S4

Absent Amino Acids

Common Amino Acids L

Mass 31894.17

PI 8.82

Basic Residues 25

Acidic Residues 18

Hydrophobic Residues 154

Net Charge +2

Boman Index 5.97

Hydrophobicity 0.578

Aliphatic Index 119.93

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 46075

Absorbance 280nm 144.46

Polar Residues 61

number

37

A

15

R

8

N

13

D

2

C

5

E

7

Q

31

G

5

H

22

I

40

L

5

K

2

M

11

F

21

P

23

S

16

T

7

W

5

Y

30

V

Amino Acid Distribution

A: 37 R: 15 N: 8 D: 13 C: 2 E: 5 Q: 7 G: 31 H: 5 I: 22 L: 40 K: 5 M: 2 F: 11 P: 21 S: 23 T: 16 W: 7 Y: 5 V: 30

Length

305

Formula

C1464H2327N387O401S4

Mass

31894.17

PI

8.82

Net Charge

+2

Boman Index

5.97

Hydrophobicity

0.578

Evidence 1 Activity

Source & Reference

Database Source dbACP