TPDB

3D PDB MODEL

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TPDB ID TPDB41683

Activity

Anticancer

Activity_category_statistics

Cancer-related peptides

Database_Source

dbACP

Sequence_Type

standard

Has_Modification No

Description A 290-aa standard natural anticancer peptide sequence curated from dbACP, with an available 3D structural model.

Sequence

MDIETQPTERDRSSRSSGSEQPSDPAGPEERSRSALAGRIADWVPGGRITVTLLVLLLFLLLVSTFVLKPFQIPSGSMERGLRIGDRVLVNKLAYRFDGRPQRGDVVVFDGTGLFGHGDYIKRVVGVGGDHVVCCDREGRIRVNGRSVDESAFLYPGDRPSTVGFDVVVPDGTLFVLGDHRSGSSDSRDHLGSPGGGMIPVDRLIGRADWIVWPFGHATHLDRPDAYADVPDAEAGGVSGAAGGREASAVSGPAGEREAGGDSGAAGERAAGEDSGAAGGGVRRAESVDG

FASTA

>TPDB41683|Anticancer|length=290
MDIETQPTERDRSSRSSGSEQPSDPAGPEERSRSALAGRIADWVPGGRITVTLLVLLLFLLLVSTFVLKPFQIPSGSMERGLRIGDRVLVNKLAYRFDGRPQRGDVVVFDGTGLFGHGDYIKRVVGVGGDHVVCCDREGRIRVNGRSVDESAFLYPGDRPSTVGFDVVVPDGTLFVLGDHRSGSSDSRDHLGSPGGGMIPVDRLIGRADWIVWPFGHATHLDRPDAYADVPDAEAGGVSGAAGGREASAVSGPAGEREAGGDSGAAGERAAGEDSGAAGGGVRRAESVDG

Formula C1309H2069N401O419S5

Absent Amino Acids

Common Amino Acids G

Mass 30288.56

PI 4.95

Basic Residues 38

Acidic Residues 42

Hydrophobic Residues 104

Net Charge -10

Boman Index 73.22

Hydrophobicity -0.287

Aliphatic Index 77.97

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 22585

Absorbance 280nm 74.57

Polar Residues 46

number

25

A

29

R

2

N

27

D

2

C

15

E

4

Q

47

G

6

H

10

I

20

L

3

K

3

M

10

F

17

P

25

S

9

T

3

W

4

Y

29

V

Amino Acid Distribution

A: 25 R: 29 N: 2 D: 27 C: 2 E: 15 Q: 4 G: 47 H: 6 I: 10 L: 20 K: 3 M: 3 F: 10 P: 17 S: 25 T: 9 W: 3 Y: 4 V: 29

Length

290

Formula

C1309H2069N401O419S5

Mass

30288.56

PI

4.95

Net Charge

-10

Boman Index

73.22

Hydrophobicity

-0.287

Evidence 1 Activity

Source & Reference

Database Source dbACP