TPDB

3D PDB MODEL

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TPDB ID TPDB41678

Activity

Anticancer

Activity_category_statistics

Cancer-related peptides

Database_Source

dbACP

Sequence_Type

standard

Has_Modification No

Description A 251-aa standard natural anticancer peptide sequence curated from dbACP, with an available 3D structural model.

Sequence

MDDPPAWIAEFTVTPKEFAAHLDAIVGSGRTPVTIGVLADHLAGRAPLPPRPVLLTFDDGFADLPGPTAEALAERSLPATAYLTTGAIVPGGRSLLPPAPMMTLAAVAGLERSGMEIGSHTVTHAQLDTLPGTDLAYELRTSKAVLEDALGHPVRHLAYPHGYNSAKVRSWSARAGYETATAVRHALSSERDERYRIARLIVRRGHTVADVESWLAGGGVRTAPYRDGPKTVAWRWYRRGRAMVRGPEFAG

FASTA

>TPDB41678|Anticancer|length=251
MDDPPAWIAEFTVTPKEFAAHLDAIVGSGRTPVTIGVLADHLAGRAPLPPRPVLLTFDDGFADLPGPTAEALAERSLPATAYLTTGAIVPGGRSLLPPAPMMTLAAVAGLERSGMEIGSHTVTHAQLDTLPGTDLAYELRTSKAVLEDALGHPVRHLAYPHGYNSAKVRSWSARAGYETATAVRHALSSERDERYRIARLIVRRGHTVADVESWLAGGGVRTAPYRDGPKTVAWRWYRRGRAMVRGPEFAG

Formula C1201H1890N352O346S5

Absent Amino Acids C

Common Amino Acids A

Mass 26956.67

PI 9.38

Basic Residues 37

Acidic Residues 26

Hydrophobic Residues 109

Net Charge +3

Boman Index 45.13

Hydrophobicity -0.174

Aliphatic Index 83.71

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 39420

Absorbance 280nm 146.23

Polar Residues 42

number

37

A

24

R

1

N

13

D

0

C

13

E

1

Q

24

G

9

H

7

I

24

L

4

K

5

M

5

F

21

P

12

S

20

T

5

W

8

Y

18

V

Amino Acid Distribution

A: 37 R: 24 N: 1 D: 13 C: 0 E: 13 Q: 1 G: 24 H: 9 I: 7 L: 24 K: 4 M: 5 F: 5 P: 21 S: 12 T: 20 W: 5 Y: 8 V: 18

Length

251

Formula

C1201H1890N352O346S5

Mass

26956.67

PI

9.38

Net Charge

+3

Boman Index

45.13

Hydrophobicity

-0.174

Evidence 1 Activity

Source & Reference

Database Source dbACP