TPDB

3D PDB MODEL

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TPDB ID TPDB41673

Activity

Anticancer

Activity_category_statistics

Cancer-related peptides

Database_Source

dbACP

Sequence_Type

standard

Has_Modification No

Description A 267-aa standard natural anticancer peptide sequence curated from dbACP, with an available 3D structural model.

Sequence

MCRHLAYVGPAEPLGGLLVAPPHALYRQSWAPRHQRHGTVNADGFGVGWYAEGDPVPARYRRAGPIWADQSFADLARVVRAGALLAAVRDATLAGADAEAAAAPFAAGAWLFSHNGAVGGWPGSLAPVAAALPPEELLSLEARNDSALVWALVLSRLRAGDDEGRALAETVLEVAAAAPASRLNLLLSNGTTVTATTWGDTLWYLTRPGAGGTVVASEPYDDDPGWQQVPDRTLLTATRTDVLLTPLKDPGEPAPADAVATEKEPRT

FASTA

>TPDB41673|Anticancer|length=267
MCRHLAYVGPAEPLGGLLVAPPHALYRQSWAPRHQRHGTVNADGFGVGWYAEGDPVPARYRRAGPIWADQSFADLARVVRAGALLAAVRDATLAGADAEAAAAPFAAGAWLFSHNGAVGGWPGSLAPVAAALPPEELLSLEARNDSALVWALVLSRLRAGDDEGRALAETVLEVAAAAPASRLNLLLSNGTTVTATTWGDTLWYLTRPGAGGTVVASEPYDDDPGWQQVPDRTLLTATRTDVLLTPLKDPGEPAPADAVATEKEPRT

Formula C1249H1939N355O372S2

Absent Amino Acids

Common Amino Acids A

Mass 27944.41

PI 4.83

Basic Residues 26

Acidic Residues 30

Hydrophobic Residues 124

Net Charge -9

Boman Index 35.98

Hydrophobicity -0.057

Aliphatic Index 89.03

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 58440

Absorbance 280nm 209.13

Polar Residues 45

number

51

A

19

R

5

N

17

D

1

C

13

E

5

Q

25

G

5

H

1

I

32

L

2

K

1

M

4

F

23

P

10

S

18

T

9

W

6

Y

20

V

Amino Acid Distribution

A: 51 R: 19 N: 5 D: 17 C: 1 E: 13 Q: 5 G: 25 H: 5 I: 1 L: 32 K: 2 M: 1 F: 4 P: 23 S: 10 T: 18 W: 9 Y: 6 V: 20

Length

267

Formula

C1249H1939N355O372S2

Mass

27944.41

PI

4.83

Net Charge

-9

Boman Index

35.98

Hydrophobicity

-0.057

Evidence 1 Activity

Source & Reference

Database Source dbACP