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Peptide record

TPDB41649

Anticancer Tumor-homing Peptides standard
6 amino acids
Basic Information
3D PDB MODEL
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TPDB41649
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 6-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
N-terminal: N -terminal modification for pentameric form
Sequence
MARAKE
Physicochemical Analysis
C28H52N10O9S1
NDCQGHILFPSTWYV
A
704.84
10.09
2
1
3
+1
3.25
-1.067
33.33
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
2
A
1
R
0
N
0
D
0
C
1
E
0
Q
0
G
0
H
0
I
0
L
1
K
1
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 1 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 1 M: 1 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
6
C28H52N10O9S1
704.84
10.09
+1
3.25
-1.067
N -terminal modification for pentameric form
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Targeting & further studied
Human breast and ovarian adenocarcinomas
ErbB-2

Source & Reference

TumorHoPe2.0
TumorHoPe2
Selection of peptides and synthesis of pentameric peptabody molecules reacting specifically with ErbB-2 receptor
2001
Houimel M et al. Int J Cancer. 2001 Jun 1 92(5):748-55.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
SK-BR-3, MDA-MB-468, OVCAR4
Phage display library
Additional Detail Fields 1 fields
SK-BR-3, MDA-MB-468, OVCAR4