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Peptide record

TPDB41605

Clone G3-A40 Anticancer Tumor-homing Peptides standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB41605
Clone G3-A40
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 15-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
Sequence
LYPLHTYTPLSLPLF
Physicochemical Analysis
C89H131N17O21
ARNDCEQGIKMWV
L
1775.12
7.71
1
0
8
+0
-3.09
0.600
130.00
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
2980
167.88
5
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
1
H
0
I
5
L
0
K
0
M
1
F
3
P
1
S
2
T
0
W
2
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 0 L: 5 K: 0 M: 0 F: 1 P: 3 S: 1 T: 2 W: 0 Y: 2 V: 0
Chemical Descriptors
15
C89H131N17O21
1775.12
7.71
+0
-3.09
0.600
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Endothelial cell and tumor cell
Targeting
Tumor metastasis
Galectin-3

Source & Reference

TumorHoPe2.0
TumorHoPe2
Peptides specific to the galectin-3 carbohydrate recognition domain inhibit metastasis-associated cancer cell adhesion
2005
Zou J et al. Carcinogenesis. 2005 Feb 26(2):309-18.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Human breast cancer cell lines BT549, express detectable levels of galectin-3, BT549trans express galactein 8
Phage display library
f88 phage/15mer peptide library and f88 phage/Cys6 mer peptide library
Additional Detail Fields 2 fields
Human breast cancer cell lines BT549, express detectable levels of galectin-3, BT549trans express galactein 8
f88 phage/15mer peptide library and f88 phage/Cys6 mer peptide library