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Peptide record

TPDB41590

GFP-peptide fusion proteins LTVSPWY-PEG-CS Anticancer Tumor-homing Peptides standard
7 amino acids
Basic Information
3D PDB MODEL
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TPDB41590
GFP-peptide fusion proteins LTVSPWY-PEG-CS
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 7-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
Sequence
LTVSPWY
Physicochemical Analysis
C43H60N8O11
ARNDCEQGHIKMF
LPSTWYV
865.00
5.94
0
0
4
-0
-2.56
0.386
97.14
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
6990
808.10
3
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
1
L
0
K
0
M
0
F
1
P
1
S
1
T
1
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 0 M: 0 F: 0 P: 1 S: 1 T: 1 W: 1 Y: 1 V: 1
Chemical Descriptors
7
C43H60N8O11
865.00
5.94
-0
-2.56
0.386
Evidence Records 2 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Targeting
Breast cancer
ErbB2

Source & Reference

TumorHoPe2.0
TumorHoPe2
Identification of novel carrier peptides for the specific delivery of therapeutics into cancer cells
2002
Shadidi M et al. FASEB J. 2003 Feb 17(2):256-8.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
The breast cancer cell lines SK-BR-3, T47D, PM1,HT2933.
Phage display library
M13 phage/7 mer peptide library
GFP
Evidence 2 Activity

Activity

Tumor-homing Peptides

Target

SKOV-3
Homing
HER2-positive tumor
HER2

Source & Reference

TumorHoPe2.0
TumorHoPe2
Actively-targeted LTVSPWY peptide-modified magnetic nanoparticles for tumor imaging
2012
Li-Yong Jie et al. Int J Nanomedicine. 2012:7:3981-9.

Other

SKOV-3 human ovarian carcinoma cell line , A549 human lung carcinoma (alveolar type 2)
flank of male BALB/C+nu/F1 nude mice
Synthetic
PEGylated chitosan
Additional Detail Fields 4 fields
GFP PEGylated chitosan
The breast cancer cell lines SK-BR-3, T47D, PM1,HT2933. SKOV-3 human ovarian carcinoma cell line , A549 human lung carcinoma (alveolar type 2)
flank of male BALB/C+nu/F1 nude mice
M13 phage/7 mer peptide library