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Peptide record

TPDB41583

Sample Peptide 1 from US011339203B2 Anticancer standard
34 amino acids
Basic Information
3D PDB MODEL
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TPDB41583
Sample Peptide 1 from US011339203B2
Anticancer
Cancer-related peptides
CancerPPD 2.0
standard
No
A 34-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
C-terminal: Amidation
Sequence
LTSVVFILICCFHLENIFVLLKKRTLRKNDRKKR-NH2
Physicochemical Analysis
C190H323N55O44S2
AQGMPWY
L
4146.12
11.04
10
2
15
+7
5.70
0.159
128.82
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
125
3.01
7
Residue Composition
number
0
A
4
R
2
N
1
D
2
C
1
E
0
Q
0
G
1
H
3
I
6
L
5
K
0
M
3
F
0
P
1
S
2
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 0 R: 4 N: 2 D: 1 C: 2 E: 1 Q: 0 G: 0 H: 1 I: 3 L: 6 K: 5 M: 0 F: 3 P: 0 S: 1 T: 2 W: 0 Y: 0 V: 3
Chemical Descriptors
34
C190H323N55O44S2
4146.12
11.04
+7
5.70
0.159
Amidation
L
Linear
Free
Anticancer
Synthetic
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell Viability
Cell Viability = 48% at 25 µM
Anticancer

Target

Renal Cancer
CAKI-2
Kidney

Assay & Model

CCK-8 assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2022
US011339203B2

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.