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Peptide record

TPDB41579

DI Anticancer standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB41579
DI
Anticancer
Cancer-related peptides
AntiCP 2.0 CancerPPD 2.0 Peptipedia SATPdb dbACP iACP-DRLF
standard
No
A 12-aa standard natural anticancer peptide sequence curated from AntiCP 2.0, CancerPPD 2.0, Peptipedia, and other sources, with an available 3D structural model.
Sequence
LTFEHYWAQLTS
Physicochemical Analysis
C71H98N16O20
RNDCGIKMPV
LT
1495.65
5.13
1
1
6
-1
-1.24
-0.200
73.33
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
6990
467.35
5
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
1
E
1
Q
0
G
1
H
0
I
2
L
0
K
0
M
1
F
0
P
1
S
2
T
1
W
1
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 1 G: 0 H: 1 I: 0 L: 2 K: 0 M: 0 F: 1 P: 0 S: 1 T: 2 W: 1 Y: 1 V: 0
Chemical Descriptors
12
C71H98N16O20
1495.65
5.13
-1
-1.24
-0.200
Free
L
Linear
Free
Antitumor
E3 ubiquitin-protein ligase
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
IC50 =0.29 µM
Anticancer
0.29 µM

Target

Colon Cancer
HCT-116-p53+/+
Colon

Assay & Model

Immunoprecipitation assay
Not Available

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2011

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
IC50 =1.6 µM
Anticancer
1.6 µM

Target

Colon Cancer
HCT-116-p53+/+
Colon

Assay & Model

Immunoprecipitation assay
Not Available

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2011