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Peptide record

TPDB41560

HM-10/10 Anticancer standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB41560
HM-10/10
Anticancer
Cancer-related peptides
CancerPPD 2.0
standard
No
A 20-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
C-terminal: Amidation N-terminal: Acetylation
Sequence
Ac-LRKLRKRLLRLVGRQLEEFL-NH2
Physicochemical Analysis
C115H206N38O26
ANDCHIMPSTWY
L
2537.14
12.24
7
2
9
+5
5.68
-0.380
151.00
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
0
A
5
R
0
N
0
D
0
C
2
E
1
Q
1
G
0
H
0
I
7
L
2
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 5 N: 0 D: 0 C: 0 E: 2 Q: 1 G: 1 H: 0 I: 0 L: 7 K: 2 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
20
C115H206N38O26
2537.14
12.24
+5
5.68
-0.380
Amidation
L
Linear
Acetylation
Anti-inflammatory and Anticancer
Synthetic
Evidence Records 1 records
Evidence 1 Activity

Activity

~60% cell viability at 10 µg/mL
Anticancer

Target

Colorectal Cancer
CT-26
Colon

Assay & Model

MTS assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2020

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.