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Peptide record

TPDB41526

hP8 Anticancer standard
28 amino acids
Basic Information
3D PDB MODEL
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TPDB41526
hP8
Anticancer
Cancer-related peptides
ACP740 _ACP240 AntiCP 2.0 CancerPPD 2.0 Peptipedia SATPdb dbACP iACP-DRLF pep-lab
standard
No
A 28-aa standard natural anticancer peptide sequence curated from ACP740 _ACP240, AntiCP 2.0, CancerPPD 2.0, and other sources, with an available 3D structural model.
Sequence
LGQSAASAHHAYIVLAIENSFMTASKKK
Physicochemical Analysis
C132H213N37O39S1
RDCPW
A
2974.43
10.06
5
1
14
+2
3.59
0.075
87.50
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
1490
50.09
8
Residue Composition
number
6
A
0
R
1
N
0
D
0
C
1
E
1
Q
1
G
2
H
2
I
2
L
3
K
1
M
1
F
0
P
4
S
1
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 6 R: 0 N: 1 D: 0 C: 0 E: 1 Q: 1 G: 1 H: 2 I: 2 L: 2 K: 3 M: 1 F: 1 P: 0 S: 4 T: 1 W: 0 Y: 1 V: 1
Chemical Descriptors
28
C132H213N37O39S1
2974.43
10.06
+2
3.59
0.075
Free
L
Linear
Free
Antiangiogenesis
Human endostatin peptides
Evidence Records 1 records
Evidence 1 Activity

Activity

No inhibition at 7 mg/kg/d
Anticancer

Target

Pancreatic Cancer
BxPC-3
Pancreatic

Assay & Model

Matrigel Assay
672-h

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2005

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.