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Peptide record

TPDB41523

Sample Peptide 7 from US011339203B2 Anticancer standard
34 amino acids
Basic Information
3D PDB MODEL
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TPDB41523
Sample Peptide 7 from US011339203B2
Anticancer
Cancer-related peptides
CancerPPD 2.0
standard
No
A 34-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
C-terminal: Amidation
Sequence
LFRAEYFLVLAVLNSGTNPIIKKRTLRKNDRKKR-NH2
Physicochemical Analysis
C184H313N57O46
CQHMW
RLK
4059.86
11.90
10
2
14
+8
7.56
-0.571
103.24
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
1490
36.70
7
Residue Composition
number
2
A
5
R
3
N
1
D
0
C
1
E
0
Q
1
G
0
H
2
I
5
L
5
K
0
M
2
F
1
P
1
S
2
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 2 R: 5 N: 3 D: 1 C: 0 E: 1 Q: 0 G: 1 H: 0 I: 2 L: 5 K: 5 M: 0 F: 2 P: 1 S: 1 T: 2 W: 0 Y: 1 V: 2
Chemical Descriptors
34
C184H313N57O46
4059.86
11.90
+8
7.56
-0.571
Amidation
L
Linear
Free
Anticancer
Synthetic
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell Viability
Cell Viability = 66.3% at 25 µM
Anticancer

Target

Renal Cancer
CAKI-2
Kidney

Assay & Model

CCK-8 assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2022
US011339203B2

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.