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Peptide record

TPDB41493

HCC79 Anti-inflammatory Anticancer Tumor-homing Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB41493
HCC79
Anti-inflammatory Anticancer Tumor-homing Peptides
Cancer-related peptides Immunity and inflammation peptides
AIPpred Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 12-aa standard natural multi-activity (Anti-inflammatory, Anticancer, and Tumor-homing Peptides) peptide sequence curated from AIPpred, Peptipedia, StackTHP, and other sources, with an available 3D structural model.
N-terminal: Acetylation
Sequence
Ac-KSLSRHDHIHHH
Physicochemical Analysis
C64H98N26O17
ANCEQGMFPTWYV
H
1503.65
10.09
7
1
2
+1
7.22
-1.767
65.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
2
Residue Composition
number
0
A
1
R
0
N
1
D
0
C
0
E
0
Q
0
G
5
H
1
I
1
L
1
K
0
M
0
F
0
P
2
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 0 H: 5 I: 1 L: 1 K: 1 M: 0 F: 0 P: 0 S: 2 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
12
C64H98N26O17
1503.65
10.09
+1
7.22
-1.767
Acetylation
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Homing
Hepatocellular carcinoma
Her-2 and ErbB-2

Source & Reference

TumorHoPe2.0
TumorHoPe2
Targeting of hepatoma cell and suppression of tumor growth by a novel 12mer peptide fused to superantigen TSST-1
2006
Jiang YQ et al. Mol Med. 2006 Apr-Jun 12(4-6):81-7.
US 2009/0274625 A1

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Human hepatoma cell line SMMC-7721, BEL-7402, and HL-02
BABL/c mice
Phage display library
M13/ 12-mer peptide library
Toxic shock syndrome toxin 1 (TSST-1)
Toxic shock syndrome toxin 1 (TSST-1) has inbitory effect on cancer invasion
Additional Detail Fields 4 fields
Toxic shock syndrome toxin 1 (TSST-1)
Human hepatoma cell line SMMC-7721, BEL-7402, and HL-02
BABL/c mice
M13/ 12-mer peptide library