TPDB

TPDB ID TPDB41492

Activity

Anticancer

Activity_category_statistics

Cancer-related peptides

Database_Source

CancerPPD 2.0

Sequence_Type

modified_plain

Has_Modification Yes

Description A 51-aa modified anticancer peptide sequence curated from CancerPPD 2.0, without an available 3D structural model.

Modification

Modified, details unspecified

Sequence

KSCCRNTWARNCYNVCRLPGTISREICAKKCDCKIISGT<BR>TCPSDYPK

FASTA

>TPDB41492|Anticancer|length=51
KSCCRNTWARNCYNVCRLPGTISREICAKKCDCKIISGT<BR>TCPSDYPK

Formula C226H374N72O68S8

Absent Amino Acids QHMF

Common Amino Acids C

Mass 5444.38

PI 8.98

Basic Residues 10

Acidic Residues 3

Hydrophobic Residues 11

Net Charge +7

Boman Index 9.47

Hydrophobicity -0.559

Aliphatic Index 47.84

Half Life

Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min

Extinction Coefficient Cystines 8980

Absorbance 280nm 164.94

Polar Residues 21

number

2

A

5

R

3

N

2

D

8

C

1

E

0

Q

2

G

0

H

4

I

1

L

5

K

0

M

0

F

3

P

4

S

4

T

1

W

2

Y

1

V

Amino Acid Distribution

A: 2 R: 5 N: 3 D: 2 C: 8 E: 1 Q: 0 G: 2 H: 0 I: 4 L: 1 K: 5 M: 0 F: 0 P: 3 S: 4 T: 4 W: 1 Y: 2 V: 1

Length

51

Formula

C226H374N72O68S8

Mass

5444.38

PI

8.98

Net Charge

+7

Boman Index

9.47

Hydrophobicity

-0.559

Evidence 1 Activity

Source & Reference

Database Source CancerPPD 2.0

Other

Source Activity Label	Source Definition
Anticancer	CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.