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Peptide record

TPDB41471

Anticancer Tumor-homing Peptides standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB41471
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 20-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
Sequence
KRASCQNPLFSNFFVCGLSE
Physicochemical Analysis
C99H151N27O29S2
DHIMTWY
FS
2247.57
8.29
2
1
7
+1
1.00
0.010
58.50
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
125
5.56
8
Residue Composition
number
1
A
1
R
2
N
0
D
2
C
1
E
1
Q
1
G
0
H
0
I
2
L
1
K
0
M
3
F
1
P
3
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 1 N: 2 D: 0 C: 2 E: 1 Q: 1 G: 1 H: 0 I: 0 L: 2 K: 1 M: 0 F: 3 P: 1 S: 3 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
20
C99H151N27O29S2
2247.57
8.29
+1
1.00
0.010
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Homing (Phage display clone)
Breast cancer

Source & Reference

TumorHoPe2.0
TumorHoPe2
Selection of tumor-binding ligands in cancer patients with phage display libraries
2006
Krag DN et al. Cancer Res. 2006 Aug 1 66(15):7724-33.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Patient biopsies, cancer cell line (breast: SK-BR-3), T47D, BT474, MDA-MB-231 and MDA-MB-361
Phage display library
M13 phage/Random 20 mer (X4CX10CX4) peptide library
Additional Detail Fields 2 fields
Patient biopsies, cancer cell line (breast: SK-BR-3), T47D, BT474, MDA-MB-231 and MDA-MB-361
M13 phage/Random 20 mer (X4CX10CX4) peptide library