Back to search

Peptide record

TPDB41454

NKL-WT Anticancer standard
27 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB41454
NKL-WT
Anticancer
Cancer-related peptides
CancerPPD 2.0
standard
No
A 27-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
Sequence
KLKSKLMVVCNKIGLLKSLCRKFVKSH
Physicochemical Analysis
C140H250N40O32S3
ADEQPTWY
K
3101.95
10.91
9
0
11
+8
4.78
0.167
118.89
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
125
4.03
6
Residue Composition
number
0
A
1
R
1
N
0
D
2
C
0
E
0
Q
1
G
1
H
1
I
5
L
7
K
1
M
1
F
0
P
3
S
0
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 0 R: 1 N: 1 D: 0 C: 2 E: 0 Q: 0 G: 1 H: 1 I: 1 L: 5 K: 7 M: 1 F: 1 P: 0 S: 3 T: 0 W: 0 Y: 0 V: 3
Chemical Descriptors
27
C140H250N40O32S3
3101.95
10.91
+8
4.78
0.167
Free
L
Linear
Free
Antimicrobial
Trematomus bernacchii
Evidence Records 1 records
Evidence 1 Activity

Activity

ATP level
ATP level = 0.753 ± 0.254 at 40 µM
Anticancer

Target

Skin Cancer
B16-F10
Skin

Assay & Model

luciferase-based ATPlite assay
12-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2023

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.