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Peptide record

TPDB41449

Sample Peptide 5 from EP3604345B1 Anticancer standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB41449
Sample Peptide 5 from EP3604345B1
Anticancer
Cancer-related peptides
CancerPPD 2.0
standard
No
A 13-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
C-terminal: Amidation
Sequence
KKRTLRKNDRKKR-NH2
Physicochemical Analysis
C72H139N31O18
ACEQGHIMFPSWYV
K
1727.09
12.43
9
1
1
+8
9.42
-3.185
30.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
2
Residue Composition
number
0
A
4
R
1
N
1
D
0
C
0
E
0
Q
0
G
0
H
0
I
1
L
5
K
0
M
0
F
0
P
0
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 4 N: 1 D: 1 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 5 M: 0 F: 0 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
13
C72H139N31O18
1727.09
12.43
+8
9.42
-3.185
Amidation
L
Linear
Free
Anticancer
Synthetic
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell Viability
Cell Viability = 106.5% at 25 µM
Anticancer

Target

Lung Cancer
HCC-827
Lung

Assay & Model

CCK-8 / WST-8
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2023
EP3604345B1

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.