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Peptide record

TPDB41448

PCC-1 Anticancer standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB41448
PCC-1
Anticancer
Cancer-related peptides
CancerPPD 2.0
standard
No
A 17-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
C-terminal: Amidation
Sequence
KKRKKKAFALKFVVDLI-NH2
Physicochemical Analysis
C98H170N26O20
NCEQGHMPSTWY
K
2032.59
11.19
7
1
9
+6
4.09
-0.100
114.71
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
2
A
1
R
0
N
1
D
0
C
0
E
0
Q
0
G
0
H
1
I
2
L
6
K
0
M
2
F
0
P
0
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 2 R: 1 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 2 K: 6 M: 0 F: 2 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
17
C98H170N26O20
2032.59
11.19
+6
4.09
-0.100
Amidation
L
Linear
Free
Antimicrobial
Poecilocoris lewisi
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
IC50 = 50.8 µM
Anticancer
50.8 µM

Target

Skin Cancer
SK-Mel-28
Skin

Assay & Model

MTS assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2021

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
IC50 = 57.8 µM
Anticancer
57.8 µM

Target

Skin Cancer
G361
Skin

Assay & Model

MTS assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2021