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Peptide record

TPDB41443

K4F8K4 Anticancer standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB41443
K4F8K4
Anticancer
Cancer-related peptides
CancerPPD 2.0
standard
No
A 16-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
Sequence
KKKKFFFFFFFFKKKK
Physicochemical Analysis
C120H170N24O17
ARNDCEQGHILMPSTWYV
KF
2220.82
11.36
8
0
8
+8
-1.12
-0.550
0.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
8
K
0
M
8
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 8 M: 0 F: 8 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
16
C120H170N24O17
2220.82
11.36
+8
-1.12
-0.550
Free
L
Linear
Free
Antimicrobial
Synthetic
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
IC50 = 571.87 ± 66.23 µg/mL
Anticancer
571.87

Target

Lung Cancer
A-549
Lung

Assay & Model

CCK-8 assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2022

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.