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Peptide record

TPDB41442

di-PST13-RK-K Anticancer standard
27 amino acids
Basic Information
3D PDB MODEL
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TPDB41442
di-PST13-RK-K
Anticancer
Cancer-related peptides
CancerPPD 2.0 Peptipedia SATPdb dbACP
standard
No
A 27-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, Peptipedia, SATPdb, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
KKKFPWWWPFKKKKKKFPWWWPFKKKK-NH2
Physicochemical Analysis
C200H282N46O28
ARNDCEQGHILMSTYV
K
3778.73
11.59
13
0
10
+13
-0.95
-1.900
0.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
33000
873.31
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
13
K
0
M
4
F
4
P
0
S
0
T
6
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 13 M: 0 F: 4 P: 4 S: 0 T: 0 W: 6 Y: 0 V: 0
Chemical Descriptors
27
C200H282N46O28
3778.73
11.59
+13
-0.95
-1.900
Amidation
L
Linear
Free
Antimicrobial
Derivative of tritrpticin
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
IC50 =15 µg/ml
Anticancer
15 µg/mL

Target

Lung Cancer
A-549
Lung

Assay & Model

MTT/MTS assay

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2008

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
IC50 =10 µg/ml
Anticancer
10 µg/mL

Target

Breast Cancer
MDA-MB-361
Breast

Assay & Model

MTT/MTS assay

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2008