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Peptide record

TPDB41424

P-5n (Lys480?â?ó?ó?ÇÜ?¼?ó?é¼?¥Lys487) Anticancer Tumor-homing Peptides standard
8 amino acids
Basic Information
3D PDB MODEL
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TPDB41424
P-5n (Lys480?â?ó?ó?ÇÜ?¼?ó?é¼?¥Lys487)
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 8-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
Sequence
KHGHGHGK
Physicochemical Analysis
C36H56N16O9
ARNDCEQILMFPSTWYV
GH
856.94
10.60
5
0
0
+2
4.89
-2.325
0.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
3
G
3
H
0
I
0
L
2
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 3 I: 0 L: 0 K: 2 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
8
C36H56N16O9
856.94
10.60
+2
4.89
-2.325
HGK
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Targeting
Breast cancer
Vitronectin

Source & Reference

TumorHoPe2.0
TumorHoPe2
Effect of His-Gly-Lys motif derived from domain 5 of high molecular weight kininogen on suppression of cancer metastasis both in vitro and in vivo
2003
Kawasaki M et al. J Biol Chem. 2003 Dec 5 278(49):49301-7.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
MDA-MB-231 cells
Natural(Kininogen protein)
Additional Detail Fields 1 fields
MDA-MB-231 cells