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Peptide record

TPDB41423

CTCE-9908 Anticancer Tumor-homing Peptides standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB41423
CTCE-9908
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 17-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
Sequence
KGVSLSYRKKGVSLSYR
Physicochemical Analysis
C86H146N26O24
ANDCEQHIMFPTW
S
1928.27
10.95
5
0
6
+5
2.27
-0.665
80.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
2980
154.54
6
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
0
I
2
L
3
K
0
M
0
F
0
P
4
S
0
T
0
W
2
Y
2
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 2 K: 3 M: 0 F: 0 P: 0 S: 4 T: 0 W: 0 Y: 2 V: 2
Chemical Descriptors
17
C86H146N26O24
1928.27
10.95
+5
2.27
-0.665
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Homing
Breast cancer
CXCR4 receptor

Source & Reference

TumorHoPe2.0
TumorHoPe2
A CXCR4 antagonist CTCE-9908 inhibits primary tumor growth and metastasis of breast cancer
2009
Huang EH et al. J Surg Res. 2009 Aug 155(2):231-6.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
MDA-231humanbreast adenocarcinoma cell line , MDA-231-BSC-12
Female athymic nude mice (4-6 weeks)
Synthetic
FITC
Additional Detail Fields 3 fields
FITC
MDA-231humanbreast adenocarcinoma cell line , MDA-231-BSC-12
Female athymic nude mice (4-6 weeks)