TPDB

3D PDB MODEL

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TPDB ID TPDB41414

Peptide_Name

Clone 109

Activity

Anticancer Tumor-homing Peptides

Activity_category_statistics

Cancer-related peptides

Database_Source

Peptipedia StackTHP StackTHPred TumorHoPe2.0

Sequence_Type

standard

Has_Modification No

Description A 9-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.

Sequence

KGCGTRQCW

FASTA

>TPDB41414|Anticancer;Tumor-homing Peptides|length=9
KGCGTRQCW

Formula C42H67N15O12S2

Absent Amino Acids ANDEHILMFPSYV

Common Amino Acids CG

Mass 1038.21

PI 9.15

Basic Residues 2

Acidic Residues 0

Hydrophobic Residues 1

Net Charge +2

Boman Index 0.21

Hydrophobicity -1.033

Aliphatic Index 0.00

Half Life

Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min

Extinction Coefficient Cystines 5625

Absorbance 280nm 541.80

Polar Residues 4

number

0

A

1

R

0

N

0

D

2

C

0

E

1

Q

2

G

0

H

0

I

0

L

1

K

0

M

0

F

0

P

0

S

1

T

1

W

0

Y

0

V

Amino Acid Distribution

A: 0 R: 1 N: 0 D: 0 C: 2 E: 0 Q: 1 G: 2 H: 0 I: 0 L: 0 K: 1 M: 0 F: 0 P: 0 S: 0 T: 1 W: 1 Y: 0 V: 0

Length

9

Formula

C42H67N15O12S2

Mass

1038.21

PI

9.15

Net Charge

+2

Boman Index

0.21

Hydrophobicity

-1.033

Evidence 1 Activity

Activity

Detail Source Activity Tumor-homing Peptides

Target

Homing or Targeting Homing (Phage display clone)

Target Tumor Mouse melanoma tumor

Source & Reference

Database Source TumorHoPe2.0

Source TumorHoPe2

Title NGR receptor and methods of identifying tumor homing molecules that home to angiogenic vasculature using same

Year 1998

Patent US 6,180,084 B1

Other

Source Activity Label	Source Definition
Tumor-homing Peptides	TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.

InVivo Model Mice bearing B16B15b Melanoma

Source Type Phage display library

Phage Display Library M13 phage /CX5 C , CX 6C ) or CX7C peptide library

Evidence 2 Activity

Activity

Detail Source Activity Tumor-homing Peptides

Target

Homing or Targeting Homing (Phage display clone)

Target Tumor Human Kaposi's Sarcoma

Source & Reference

Database Source TumorHoPe2.0

Source TumorHoPe2

Title NGR receptor and methods of identifying tumor homing molecules that home to angiogenic vasculature using same

Year 1998

Patent US 6,180,084 B1

Other

InVivo Model Mice bearing a SLK human Kaposi's sarcoma.

Source Type Phage display library

Phage Display Library M13 phage /CX5 C , CX 6C ) or CX7C peptide library

InVivo_Model

Mice bearing B16B15b Melanoma Mice bearing a SLK human Kaposi's sarcoma.

Phage_Display_Library

M13 phage /CX5 C , CX 6C ) or CX7C peptide library