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Peptide record

TPDB41405

LfcinB-P13 Anticancer standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB41405
LfcinB-P13
Anticancer
Cancer-related peptides
CancerPPD 2.0
standard
No
A 13-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
Sequence
KCRRWLKRMKKLG
Physicochemical Analysis
C75H135N27O14S2
ANDEQHIFPSTYV
K
1703.19
12.16
7
0
4
+7
2.96
-1.415
60.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
322.92
1
Residue Composition
number
0
A
3
R
0
N
0
D
1
C
0
E
0
Q
1
G
0
H
0
I
2
L
4
K
1
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 1 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 2 K: 4 M: 1 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
13
C75H135N27O14S2
1703.19
12.16
+7
2.96
-1.415
Free
L
Linear
Free
Anticancer
Synthetic analog of LFcinB
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
IC50 = 41.8 µg/ml
Anticancer
41.8 µg/mL

Target

Liver Cancer
SMMC-7721
Liver

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2017

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.