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Peptide record

TPDB41403

Anticancer Tumor-homing Peptides standard
6 amino acids
Basic Information
3D PDB MODEL
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TPDB41403
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 6-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
Sequence
KCCYSL
Physicochemical Analysis
C30H49N7O9S2
ARNDEQGHIMFPTWV
C
715.88
8.28
1
0
2
+1
-0.86
0.467
65.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
1615
225.60
4
Residue Composition
number
0
A
0
R
0
N
0
D
2
C
0
E
0
Q
0
G
0
H
0
I
1
L
1
K
0
M
0
F
0
P
1
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 1 M: 0 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
6
C30H49N7O9S2
715.88
8.28
+1
-0.86
0.467
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Homing
Human breast carcinoma
ErbB-2

Source & Reference

TumorHoPe2.0
TumorHoPe2
Evaluation of an 111In-radiolabeled peptide as a targeting and imaging agent for ErbB-2 receptor expressing breast carcinomas
2007
Kumar SR et al. Clin Cancer Res. 2007 Oct 15 13(20):6070-9.
US 2010/0061930

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
MDA-MB,Human breast carcinoma cell line, Prostate carcinoma cell line (PC-3),K-562 human erythroid leukemia cell line
SCID mice, MDA-MB-435 breast carcinoma cell
Phage display library
111In-DOTA, Biotin
Additional Detail Fields 3 fields
111In-DOTA, Biotin
MDA-MB,Human breast carcinoma cell line, Prostate carcinoma cell line (PC-3),K-562 human erythroid leukemia cell line
SCID mice, MDA-MB-435 breast carcinoma cell