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Peptide record

TPDB41401

Tat-a5 Anticancer standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB41401
Tat-a5
Anticancer
Cancer-related peptides
ACP740 _ACP240 AntiCP 2.0 CancerPPD 2.0 Peptipedia SATPdb dbACP iACP-DRLF
standard
No
A 22-aa standard natural anticancer peptide sequence curated from ACP740 _ACP240, AntiCP 2.0, CancerPPD 2.0, and other sources, with an available 3D structural model.
Sequence
KAQIRAMECNILGRKKRRQRRR
Physicochemical Analysis
C113H211N49O28S2
DHFPSTWYV
R
2768.35
12.53
10
1
6
+9
10.26
-1.673
62.27
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
4
Residue Composition
number
2
A
7
R
1
N
0
D
1
C
1
E
2
Q
1
G
0
H
2
I
1
L
3
K
1
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 7 N: 1 D: 0 C: 1 E: 1 Q: 2 G: 1 H: 0 I: 2 L: 1 K: 3 M: 1 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
22
C113H211N49O28S2
2768.35
12.53
+9
10.26
-1.673
Free
L
Linear
Free
Anticancer
HIV-Tat (49-57)
Evidence Records 1 records
Evidence 1 Activity

Activity

~80% Cytotoxicity at 100 µM
Anticancer

Target

Colon Cancer
HCT-116
Colon

Assay & Model

MTT/MTS assay
24-h

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2008

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.