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Peptide record

TPDB41391

Z3 Anticancer standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB41391
Z3
Anticancer
Cancer-related peptides
ACP740 _ACP240 AntiCP 2.0 CancerPPD 2.0 Peptipedia SATPdb dbACP iACP-DRLF pep-lab
standard
No
A 22-aa standard natural anticancer peptide sequence curated from ACP740 _ACP240, AntiCP 2.0, CancerPPD 2.0, and other sources, with an available 3D structural model.
Sequence
KAAKKAWKAWKKAAKAAWKKAA
Physicochemical Analysis
C117H190N34O23
RNDCEQGHILMFPSTYV
A
2441.01
11.41
9
0
13
+9
1.66
-0.900
45.45
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
16500
675.95
0
Residue Composition
number
10
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
9
K
0
M
0
F
0
P
0
S
0
T
3
W
0
Y
0
V
Amino Acid Distribution
A: 10 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 9 M: 0 F: 0 P: 0 S: 0 T: 0 W: 3 Y: 0 V: 0
Chemical Descriptors
22
C117H190N34O23
2441.01
11.41
+9
1.66
-0.900
Free
L
Linear
Free
Anticancer
Synthetic
Evidence Records 3 records
Evidence 1 Activity

Activity

EC50
EC50 >211 µM
Anticancer
211 µM

Target

Skin Cancer
Meth A
Skin

Assay & Model

MTT/MTS assay
Not Available

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2011

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

EC50
EC50 =128 µM
Anticancer
128 µM

Target

Breast Cancer
MT-1
Breast

Assay & Model

MTT/MTS assay
Not Available

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2011
Evidence 3 Activity

Activity

EC50
EC50 >211 µM
Anticancer
211 µM

Target

Colon Cancer
HT-29
Colon

Assay & Model

MTT/MTS assay
Not Available

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2011