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Peptide record

TPDB41385

LVTX-8 Anticancer standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB41385
LVTX-8
Anticancer
Cancer-related peptides
CancerPPD 2.0
standard
No
A 25-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
C-terminal: Amidation N-terminal: Acetylation
Sequence
Ac-IWLTALKFLGKNLGKHLAKQQLSKL-NH2
Physicochemical Analysis
C135H226N36O31
RDCEMPYV
L
2849.50
11.12
6
0
12
+5
0.23
0.044
132.80
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
5500
193.02
5
Residue Composition
number
2
A
0
R
1
N
0
D
0
C
0
E
2
Q
2
G
1
H
1
I
7
L
5
K
0
M
1
F
0
P
1
S
1
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 2 G: 2 H: 1 I: 1 L: 7 K: 5 M: 0 F: 1 P: 0 S: 1 T: 1 W: 1 Y: 0 V: 0
Chemical Descriptors
25
C135H226N36O31
2849.50
11.12
+5
0.23
0.044
Amidation
L
Linear
Acetylation
Anticancer
Lycosa vittata
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
IC50 = 8 µM
Anticancer
8 µM

Target

Lung Cancer
A-549
Lung

Assay & Model

CCK-8 assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2020

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
IC50 = 19 µM
Anticancer
19 µM

Target

Lung Cancer
H-460
Lung

Assay & Model

CCK-8 assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2020