Peptide record

TPDB41360

DN4 Anticancer standard
13 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB41360
DN4
Anticancer
Cancer-related peptides
CancerPPD 2.0
standard
No
A 13-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
Sequence
ILGKIWKGIVSDF
Physicochemical Analysis
C72H114N16O17
ARNCEQHMPTY
I
1475.79
9.88
2
1
7
+1
-1.04
0.808
142.31
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
5500
372.68
1
Residue Composition
number
0
A
0
R
0
N
1
D
0
C
0
E
0
Q
2
G
0
H
3
I
1
L
2
K
0
M
1
F
0
P
1
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 3 L: 1 K: 2 M: 0 F: 1 P: 0 S: 1 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
13
C72H114N16O17
1475.79
9.88
+1
-1.04
0.808
Free
L
Linear
Free
Antimicrobial
Synthetic
Evidence Records 1 records
Evidence 1 Activity

Activity

191.67 ± 12.02 µM
Anticancer

Target

Liver Cancer
HepG-2
Liver

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2021

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.