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Peptide record

TPDB41333

Anticancer Tumor-homing Peptides standard
7 amino acids
Basic Information
3D PDB MODEL
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TPDB41333
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 7-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
N-terminal: AD vector covalently linked at N-terminal
Sequence
HTFEPGV
Physicochemical Analysis
C36H51N9O11
ARNDCQILKMSWY
EGHFPTV
785.85
5.13
1
1
2
-1
2.52
-0.343
41.43
Mammalian: 3.5 hour Yeast: 10 min E.coli: >10 hour
0
0.00
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
1
E
0
Q
1
G
1
H
0
I
0
L
0
K
0
M
1
F
1
P
0
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 1 H: 1 I: 0 L: 0 K: 0 M: 0 F: 1 P: 1 S: 0 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
7
C36H51N9O11
785.85
5.13
-1
2.52
-0.343
AD vector covalently linked at N-terminal
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Homing
Medullary thyroid carcinoma (MTC)

Source & Reference

TumorHoPe2.0
TumorHoPe2
Discovery of targeting peptides for selective therapy of medullary thyroid carcinoma
2005
Bockmann M et al. J Gene Med. 2005 Feb 7(2):179-88.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Human TT cells, 293 cells (Ad5 E1-transformed human embryonic kidney cells), H1299 (human bronchoalveolar carcinoma) VH6 cells (human primary foreskin fibroblasts)
Mice bearing MTC tumors
Phage display library
M13 phage /C7C peptide library
Green fluorescent protein (GFP)
Additional Detail Fields 4 fields
Green fluorescent protein (GFP)
Human TT cells, 293 cells (Ad5 E1-transformed human embryonic kidney cells), H1299 (human bronchoalveolar carcinoma) VH6 cells (human primary foreskin fibroblasts)
Mice bearing MTC tumors
M13 phage /C7C peptide library