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Peptide record

TPDB41331

hP1 Anticancer standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB41331
hP1
Anticancer
Cancer-related peptides
ACP740 _ACP240 AntiCP 2.0 CancerPPD 2.0 Peptipedia SATPdb dbACP iACP-DRLF pep-lab
standard
No
A 25-aa standard natural anticancer peptide sequence curated from ACP740 _ACP240, AntiCP 2.0, CancerPPD 2.0, and other sources, with an available 3D structural model.
Sequence
HSHRDFQPVLHLVALNSPLSGGMRG
Physicochemical Analysis
C119H189N39O33S1
CEIKTWY
L
2726.11
10.89
5
1
9
+1
4.42
-0.232
89.60
Mammalian: 3.5 hour Yeast: 10 min E.coli: >10 hour
0
0.00
5
Residue Composition
number
1
A
2
R
1
N
1
D
0
C
0
E
1
Q
3
G
3
H
0
I
4
L
0
K
1
M
1
F
2
P
3
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 2 N: 1 D: 1 C: 0 E: 0 Q: 1 G: 3 H: 3 I: 0 L: 4 K: 0 M: 1 F: 1 P: 2 S: 3 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
25
C119H189N39O33S1
2726.11
10.89
+1
4.42
-0.232
Free
L
Linear
Free
Antiangiogenesis
Human endostatin peptides
Evidence Records 1 records
Evidence 1 Activity

Activity

39% inhibition at 7 mg/kg/d
Anticancer

Target

Pancreatic Cancer
BxPC-3
Pancreatic

Assay & Model

Matrigel Assay
672-h

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2005

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.