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Peptide record

TPDB41328

hP6 Anticancer standard
24 amino acids
Basic Information
3D PDB MODEL
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TPDB41328
hP6
Anticancer
Cancer-related peptides
ACP740 _ACP240 AntiCP 2.0 CancerPPD 2.0 Peptipedia SATPdb dbACP iACP-DRLF pep-lab
standard
No
A 24-aa standard natural anticancer peptide sequence curated from ACP740 _ACP240, AntiCP 2.0, CancerPPD 2.0, and other sources, with an available 3D structural model.
Sequence
HPTWPQKSVWHGSDPNGRRLTESY
Physicochemical Analysis
C126H183N39O37
ACIMF
PS
2836.08
9.74
5
2
5
+1
5.69
-1.575
28.33
Mammalian: 3.5 hour Yeast: 10 min E.coli: >10 hour
12490
440.40
8
Residue Composition
number
0
A
2
R
1
N
1
D
0
C
1
E
1
Q
2
G
2
H
0
I
1
L
1
K
0
M
0
F
3
P
3
S
2
T
2
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 2 N: 1 D: 1 C: 0 E: 1 Q: 1 G: 2 H: 2 I: 0 L: 1 K: 1 M: 0 F: 0 P: 3 S: 3 T: 2 W: 2 Y: 1 V: 1
Chemical Descriptors
24
C126H183N39O37
2836.08
9.74
+1
5.69
-1.575
Free
L
Linear
Free
Antiangiogenesis
Human endostatin peptides
Evidence Records 1 records
Evidence 1 Activity

Activity

No inhibition at 7 mg/kg/d
Anticancer

Target

Pancreatic Cancer
BxPC-3
Pancreatic

Assay & Model

Matrigel Assay
672-h

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2005

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.