Back to search

Peptide record

TPDB41322

P-5c (His488?â?ó?ó?ÇÜ?¼?ó?é¼?¥Asn495) Anticancer Tumor-homing Peptides standard
8 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB41322
P-5c (His488?â?ó?ó?ÇÜ?¼?ó?é¼?¥Asn495)
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 8-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
Sequence
HKNKGKKN
Physicochemical Analysis
C40H72N16O11
ARDCEQILMFPSTWYV
K
953.11
11.00
5
0
0
+4
5.77
-3.275
0.00
Mammalian: 3.5 hour Yeast: 10 min E.coli: >10 hour
0
0.00
2
Residue Composition
number
0
A
0
R
2
N
0
D
0
C
0
E
0
Q
1
G
1
H
0
I
0
L
4
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 2 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 1 I: 0 L: 0 K: 4 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
8
C40H72N16O11
953.11
11.00
+4
5.77
-3.275
HGK
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Targeting
Breast cancer
Vitronectin

Source & Reference

TumorHoPe2.0
TumorHoPe2
Effect of His-Gly-Lys motif derived from domain 5 of high molecular weight kininogen on suppression of cancer metastasis both in vitro and in vivo
2003
Kawasaki M et al. J Biol Chem. 2003 Dec 5 278(49):49301-7.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
MDA-MB-231 cells
Natural(Kininogen protein)
Additional Detail Fields 1 fields
MDA-MB-231 cells