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Peptide record

TPDB41310

P30 Anticancer Tumor-homing Peptides standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB41310
P30
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 15-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
C-terminal: C-terminal modification with addition of polylysine to form MAP
Sequence
HGRFILPWWYAFSPS
Physicochemical Analysis
C94H122N22O19
NDCEQKMTV
FPSW
1864.14
9.88
2
0
8
+1
-5.00
-0.020
58.67
Mammalian: 3.5 hour Yeast: 10 min E.coli: >10 hour
12490
670.01
3
Residue Composition
number
1
A
1
R
0
N
0
D
0
C
0
E
0
Q
1
G
1
H
1
I
1
L
0
K
0
M
2
F
2
P
2
S
0
T
2
W
1
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 1 I: 1 L: 1 K: 0 M: 0 F: 2 P: 2 S: 2 T: 0 W: 2 Y: 1 V: 0
Chemical Descriptors
15
C94H122N22O19
1864.14
9.88
+1
-5.00
-0.020
C-terminal modification with addition of polylysine to form MAP
W-Y-A-W/F-S-P
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Targeting
Breast cancer
Gal beta1 --> 3GalNAc alpha disaccharide

Source & Reference

TumorHoPe2.0
TumorHoPe2
Characterization of peptides that bind the tumor-associated Thomsen-Friedenreich antigen selected from bacteriophage display libraries
1997
Peletskaya EN et al. J Mol Biol. 1997 Jul 18 270(3):374-84.
US 2004/0010116 A1

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
MDA-MB-435 breast carcinoma cells
Phage display library
f3 Bacteriophage/ 15-mer peptide library
FITC
Additional Detail Fields 3 fields
FITC
MDA-MB-435 breast carcinoma cells
f3 Bacteriophage/ 15-mer peptide library