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Peptide record

TPDB41305

dipeptidyl peptidase IV inhibitor (DPP IV inhibitor) Anticancer iDPPIV standard
2 amino acids
Basic Information
3D PDB MODEL
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TPDB41305
dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
Anticancer iDPPIV
Cardiometabolic peptides Cancer-related peptides
CancerPPD 2.0 iDPPIV Peptipedia
standard
No
A 2-aa standard natural multi-activity (Anticancer and iDPPIV) peptide sequence curated from CancerPPD 2.0, iDPPIV, and Peptipedia, with an available 3D structural model.
Sequence
HE
Physicochemical Analysis
C11H16N4O5
ARNDCQGILKMFPSTWYV
EH
284.27
5.13
1
1
0
-1
2.98
-3.350
0.00
Mammalian: 3.5 hour Yeast: 10 min E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
1
E
0
Q
0
G
1
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 0 H: 1 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
2
C11H16N4O5
284.27
5.13
-1
2.98
-3.350
284.2679
284.1117
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
iDPPIV
0.00 µM
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
dipeptidyl peptidase IV inhibitor
dpp

Source & Reference

iDPPIV
Lan V. T. T., Ito K., Ohno M., Motoyama T., Ito S., Kawarasaki Y.
Analyzing a dipeptide library to identify human dipeptidyl peptidase IV inhibitor. Food Chemistry 175, 66-73, 2015
2015
Journal

Other

2
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@H](CC1=CN=C[NH]1)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)O InChI=1S/C11H16N4O5/c12-7(3-6-4-13-5-14-6)10(18)15-8(11(19)20)1-2-9(16)17/h4-5,7-8H,1-3,12H2,(H,13,14)(H,15,18)(H,16,17)(H,19,20)/t7-,8-/m0/s1 InChIKey=VHOLZZKNEBBHTH-YUMQZZPRSA-N Inhibitor of Glutamate carboxypeptidase (EC 3.4.17.11) (MEROPS ID: M20.001) accordinbg to the BIOPEP-UWM database of bioactive peptides, the BRENDA database
Additional Detail Fields 1 fields
2