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Peptide record

TPDB41295

HAZ Anticancer standard
21 amino acids
Basic Information
3D PDB MODEL
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TPDB41295
HAZ
Anticancer
Cancer-related peptides
CancerPPD 2.0
standard
No
A 21-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
Sequence
GVKFAKRFWRFAKKAFKRFEK
Physicochemical Analysis
C131H199N37O24
NDCQHILMPSTY
K
2676.26
12.18
9
1
10
+8
2.46
-0.862
28.10
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
205.51
0
Residue Composition
number
3
A
3
R
0
N
0
D
0
C
1
E
0
Q
1
G
0
H
0
I
0
L
6
K
0
M
5
F
0
P
0
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 3 R: 3 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 6 M: 0 F: 5 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
21
C131H199N37O24
2676.26
12.18
+8
2.46
-0.862
Free
L
Linear
Free
Antimicrobial and Anticancer
Synthetic
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
IC50 = 5.44 µM
Anticancer
5.44 µM

Target

Lung Cancer
A-549
Lung

Assay & Model

MTT assay
4-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2022

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.