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Peptide record

TPDB41287

DC3 Anticancer Antifungal standard
30 amino acids
Basic Information
3D PDB MODEL
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TPDB41287
DC3
Anticancer Antifungal
Anti-infective peptides Cancer-related peptides
CancerPPD 2.0 Peptipedia dbACP Antifungipept
standard
No
A 30-aa standard natural multi-activity (Anticancer and Antifungal) peptide sequence curated from CancerPPD 2.0, Peptipedia, dbACP, and other sources, with an available 3D structural model.
C-terminal: Cyclized N-terminal: Cyclized
Sequence
GTSCGETCVLLPCLSSVLGCTCQNKRCYKD
Physicochemical Analysis
C129H217N37O44S6
AHIMFW
C
3182.72
7.62
3
2
7
+1
3.85
0.123
71.33
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1865
58.60
15
Residue Composition
number
0
A
1
R
1
N
1
D
6
C
1
E
1
Q
3
G
0
H
0
I
4
L
2
K
0
M
0
F
1
P
3
S
3
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 0 R: 1 N: 1 D: 1 C: 6 E: 1 Q: 1 G: 3 H: 0 I: 0 L: 4 K: 2 M: 0 F: 0 P: 1 S: 3 T: 3 W: 0 Y: 1 V: 2
Chemical Descriptors
30
C129H217N37O44S6
3182.72
7.62
+1
3.85
0.123
Cyclized
L
Cyclic
Cyclized
Anticancer
Hedyotis diffusa
Evidence Records 3 records
Evidence 1 Activity

Activity

IC50
IC50 = 0.21 µM
Anticancer
0.21 µM

Target

Prostate Cancer
LNCaP
Prostate

Assay & Model

CCK-8 assay
72-h

Source & Reference

CancerPPD 2.0 dbACP
CancerPPD2
2015

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
IC50 = 0.76 µM
Anticancer
0.76 µM

Target

Prostate Cancer
PC-3
Prostate

Assay & Model

CCK-8 assay
72-h

Source & Reference

CancerPPD 2.0 dbACP
CancerPPD2
2015
Evidence 3 Activity

Activity

IC50
IC50 = 0.55 µM
Anticancer
0.55 µM

Target

Liver Cancer
DU-145
Liver

Assay & Model

CCK-8 assay
72-h

Source & Reference

CancerPPD 2.0 dbACP
CancerPPD2
2015