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Peptide record

TPDB41276

Anticancer Tumor-homing Peptides standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB41276
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 20-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
Sequence
GSLACQNIVVCVKKQCNALC
Physicochemical Analysis
C86H152N26O26S4
RDEHMFPTWY
C
2094.55
8.31
2
0
8
+2
1.60
0.765
112.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
250
11.94
9
Residue Composition
number
2
A
0
R
2
N
0
D
4
C
0
E
2
Q
1
G
0
H
1
I
2
L
2
K
0
M
0
F
0
P
1
S
0
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 2 R: 0 N: 2 D: 0 C: 4 E: 0 Q: 2 G: 1 H: 0 I: 1 L: 2 K: 2 M: 0 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 3
Chemical Descriptors
20
C86H152N26O26S4
2094.55
8.31
+2
1.60
0.765
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Homing (Phage display clone)
Breast cancer

Source & Reference

TumorHoPe2.0
TumorHoPe2
Selection of tumor-binding ligands in cancer patients with phage display libraries
2006
Krag DN et al. Cancer Res. 2006 Aug 1 66(15):7724-33.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Patient biopsies, cancer cell line (breast: SK-BR-3), T47D, BT474, MDA-MB-231 and MDA-MB-361
Phage display library
M13 phage/Random 20 mer (X4CX10CX4) peptide library
Additional Detail Fields 2 fields
Patient biopsies, cancer cell line (breast: SK-BR-3), T47D, BT474, MDA-MB-231 and MDA-MB-361
M13 phage/Random 20 mer (X4CX10CX4) peptide library