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Peptide record

TPDB41273

hP5 Anticancer standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB41273
hP5
Anticancer
Cancer-related peptides
ACP740 _ACP240 AntiCP 2.0 CancerPPD 2.0 Peptipedia SATPdb dbACP iACP-DRLF pep-lab
standard
No
A 25-aa standard natural anticancer peptide sequence curated from ACP740 _ACP240, AntiCP 2.0, CancerPPD 2.0, and other sources, with an available 3D structural model.
Sequence
GSEGPLKPGARIFSFDGKDVLRHPT
Physicochemical Analysis
C120H189N35O35
NCQMWY
G
2682.03
9.88
5
3
7
+1
7.04
-0.620
62.40
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
1
A
2
R
0
N
2
D
0
C
1
E
0
Q
4
G
1
H
1
I
2
L
2
K
0
M
2
F
3
P
2
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 2 N: 0 D: 2 C: 0 E: 1 Q: 0 G: 4 H: 1 I: 1 L: 2 K: 2 M: 0 F: 2 P: 3 S: 2 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
25
C120H189N35O35
2682.03
9.88
+1
7.04
-0.620
Free
L
Linear
Free
Antiangiogenesis
Human endostatin peptides
Evidence Records 1 records
Evidence 1 Activity

Activity

29% inhibition at 7 mg/kg/d
Anticancer

Target

Pancreatic Cancer
BxPC-3
Pancreatic

Assay & Model

Matrigel Assay
672-h

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2005

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.