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Peptide record

TPDB41262

Anticancer Tumor-homing Peptides standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB41262
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 20-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
Sequence
GRQGCYEHLWRLIAWCAIFL
Physicochemical Analysis
C114H167N31O25S2
NDKMPSTV
L
2435.89
8.29
3
1
11
+1
-3.69
0.435
107.50
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
12615
517.88
4
Residue Composition
number
2
A
2
R
0
N
0
D
2
C
1
E
1
Q
2
G
1
H
2
I
3
L
0
K
0
M
1
F
0
P
0
S
0
T
2
W
1
Y
0
V
Amino Acid Distribution
A: 2 R: 2 N: 0 D: 0 C: 2 E: 1 Q: 1 G: 2 H: 1 I: 2 L: 3 K: 0 M: 0 F: 1 P: 0 S: 0 T: 0 W: 2 Y: 1 V: 0
Chemical Descriptors
20
C114H167N31O25S2
2435.89
8.29
+1
-3.69
0.435
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Homing (Phage display clone)
Breast cancer

Source & Reference

TumorHoPe2.0
TumorHoPe2
Selection of tumor-binding ligands in cancer patients with phage display libraries
2006
Krag DN et al. Cancer Res. 2006 Aug 1 66(15):7724-33.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Patient biopsies, cancer cell line (breast: SK-BR-3), T47D, BT474, MDA-MB-231 and MDA-MB-361
Phage display library
M13 phage/Random 20 mer (X4CX10CX4) peptide library
Additional Detail Fields 2 fields
Patient biopsies, cancer cell line (breast: SK-BR-3), T47D, BT474, MDA-MB-231 and MDA-MB-361
M13 phage/Random 20 mer (X4CX10CX4) peptide library