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Peptide record

TPDB41240

GPLPLR-Lip. DPP-CNDAC peptide Anticancer Tumor-homing Peptides standard
6 amino acids
Basic Information
3D PDB MODEL
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TPDB41240
GPLPLR-Lip. DPP-CNDAC peptide
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 6-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
GPLPLR-NH2
Physicochemical Analysis
C30H53N9O7
ANDCEQHIKMFSTWYV
LP
651.81
11.05
1
0
2
+1
0.60
-0.083
130.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
2
L
0
K
0
M
0
F
2
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 2 K: 0 M: 0 F: 0 P: 2 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
6
C30H53N9O7
651.81
11.05
+1
0.60
-0.083
Amidation
PLP
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Angiogenic endothelium cell,tumor cell.
Homing
Tumor metastasis
MT1-MMP(Membrane type 1Matrix metalloproteinase )

Source & Reference

TumorHoPe2.0
TumorHoPe2
Anti-neovascular therapy by liposomal drug targeted to membrane type-1 matrix metalloproteinase
2004
Kondo M et al. Int J Cancer. 2004 Jan 10 108(2):301-6.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
5-week-old BALB/c male mice bearing NL-17 carcinoma
Synthetic
Ribosome-encapsulated [2-18F]FDG,Lip. DPP-CNDAC peptide
Additional Detail Fields 2 fields
Ribosome-encapsulated [2-18F]FDG,Lip. DPP-CNDAC peptide
5-week-old BALB/c male mice bearing NL-17 carcinoma