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Peptide record

TPDB41208

HEH Anticancer standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB41208
HEH
Anticancer
Cancer-related peptides
CancerPPD 2.0
standard
No
A 15-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
C-terminal: Amidation
Sequence
GLLHLLELLLHAAGW-NH2
Physicochemical Analysis
C80H126N20O18
RNDCQIKMFPSTYV
L
1656.00
6.01
2
1
10
-1
-2.15
1.240
195.33
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
332.12
0
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
1
E
0
Q
2
G
2
H
0
I
7
L
0
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 2 H: 2 I: 0 L: 7 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
15
C80H126N20O18
1656.00
6.01
-1
-2.15
1.240
Amidation
L
Linear
Free
Anticancer
Synthetic
Evidence Records 3 records
Evidence 1 Activity

Activity

IC50
IC50 = 28.60 ± 10.75 µM
Anticancer
28.60

Target

Breast Cancer
HMLER
Breast

Assay & Model

MTT assay
72-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2022

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
IC50 = 10.95 ± 1.06 µM
Anticancer
10.95

Target

Breast Cancer
HMLER-shEcad
Breast

Assay & Model

MTT assay
72-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2022
Evidence 3 Activity

Activity

IC50
IC50 = 106 ± 14 µM
Anticancer
106

Target

Bone Cancer
U-2 OS
Bone

Assay & Model

MTT assay
72-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2022