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Peptide record

TPDB41203

EHK Anticancer standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB41203
EHK
Anticancer
Cancer-related peptides
CancerPPD 2.0
standard
No
A 15-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
C-terminal: Amidation
Sequence
GLLELLHLLLKAAGW-NH2
Physicochemical Analysis
C80H131N19O18
RNDCQIMFPSTYV
L
1647.04
7.82
2
1
10
+0
-2.12
1.193
195.33
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
333.93
0
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
1
E
0
Q
2
G
1
H
0
I
7
L
1
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 2 H: 1 I: 0 L: 7 K: 1 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
15
C80H131N19O18
1647.04
7.82
+0
-2.12
1.193
Amidation
L
Linear
Free
Anticancer
Synthetic
Evidence Records 3 records
Evidence 1 Activity

Activity

IC50
IC50 = 1.35 ± 0.35 µM
Anticancer
1.35

Target

Breast Cancer
HMLER
Breast

Assay & Model

MTT assay
72-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2022

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
IC50 = 0.71 ± 0.13 µM
Anticancer
0.71

Target

Breast Cancer
HMLER-shEcad
Breast

Assay & Model

MTT assay
72-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2022
Evidence 3 Activity

Activity

IC50
IC50 = 25.00 ± 0 µM
Anticancer
25.00

Target

Bone Cancer
U-2 OS
Bone

Assay & Model

MTT assay
72-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2022