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Peptide record

TPDB41190

DEH Anticancer standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB41190
DEH
Anticancer
Cancer-related peptides
CancerPPD 2.0
standard
No
A 15-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
C-terminal: Amidation
Sequence
GLLDLLELLLHAAGW-NH2
Physicochemical Analysis
C78H124N18O20
RNCQIKMFPSTYV
L
1633.95
4.06
1
2
10
-2
-1.88
1.220
195.33
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
336.61
0
Residue Composition
number
2
A
0
R
0
N
1
D
0
C
1
E
0
Q
2
G
1
H
0
I
7
L
0
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 1 C: 0 E: 1 Q: 0 G: 2 H: 1 I: 0 L: 7 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
15
C78H124N18O20
1633.95
4.06
-2
-1.88
1.220
Amidation
L
Linear
Free
Anticancer
Synthetic
Evidence Records 3 records
Evidence 1 Activity

Activity

IC50
IC50 = 5.35 ± 1.91 µM
Anticancer
5.35

Target

Breast Cancer
HMLER
Breast

Assay & Model

MTT assay
72-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2022

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
IC50 = 3.60 ± 0.42 µM
Anticancer
3.60

Target

Breast Cancer
HMLER-shEcad
Breast

Assay & Model

MTT assay
72-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2022
Evidence 3 Activity

Activity

IC50
IC50 = 36.48 ± 3.92 µM
Anticancer
36.48

Target

Bone Cancer
U-2 OS
Bone

Assay & Model

MTT assay
72-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2022