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Peptide record

TPDB41182

Aurein 1.2_mutant (Aurm) Anticancer standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB41182
Aurein 1.2_mutant (Aurm)
Anticancer
Cancer-related peptides
CancerPPD 2.0
standard
No
A 13-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
N-terminal: Acetylation
Sequence
Ac-GLFDIIKKIIKSF
Physicochemical Analysis
C75H124N16O17
ARNCEQHMPTWYV
I
1521.91
10.32
3
1
7
+2
0.28
0.846
150.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
0
A
0
R
0
N
1
D
0
C
0
E
0
Q
1
G
0
H
4
I
1
L
3
K
0
M
2
F
0
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 4 L: 1 K: 3 M: 0 F: 2 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
13
C75H124N16O17
1521.91
10.32
+2
0.28
0.846
Free
L
Linear
Acetylation
Antimicrobial
Synthetic
Evidence Records 2 records
Evidence 1 Activity

Activity

51.63% cell viability
Anticancer

Target

Colon Cancer
SW-480
Colon

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2023

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

66.10% cell viability
Anticancer

Target

Colon Cancer
HT-29
Colon

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2023