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Peptide record

TPDB41176

Poca B Anticancer standard
28 amino acids
Basic Information
3D PDB MODEL
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TPDB41176
Poca B
Anticancer
Cancer-related peptides
CancerPPD 2.0
standard
No
A 28-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
C-terminal: Cyclized N-terminal: Cyclized
Sequence
GIPCAESCVFIPCVTAILGCSCKDVCYN
Physicochemical Analysis
C124H198N30O38S6
RQHMW
C
2909.47
4.07
1
2
11
-1
0.85
1.046
93.93
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1865
64.10
11
Residue Composition
number
2
A
0
R
1
N
1
D
6
C
1
E
0
Q
2
G
0
H
3
I
1
L
1
K
0
M
1
F
2
P
2
S
1
T
0
W
1
Y
3
V
Amino Acid Distribution
A: 2 R: 0 N: 1 D: 1 C: 6 E: 1 Q: 0 G: 2 H: 0 I: 3 L: 1 K: 1 M: 0 F: 1 P: 2 S: 2 T: 1 W: 0 Y: 1 V: 3
Chemical Descriptors
28
C124H198N30O38S6
2909.47
4.07
-1
0.85
1.046
Cyclized
L
Cyclic
Cyclized
Antimicrobial,Cytotoxic
Pombalia calceolaria
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
IC50 = 2.7 µM
Anticancer
2.7 µM

Target

Breast Cancer
MDA-MB-231
Breast

Assay & Model

MTS assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2018

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.