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Peptide record

TPDB41171

Cationic Amphiphilic Anticancer standard
21 amino acids
Basic Information
3D PDB MODEL
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TPDB41171
Cationic Amphiphilic
Anticancer
Cancer-related peptides
ACP740 _ACP240 AntiCP 2.0 CancerPPD 2.0 Peptipedia SATPdb dbACP iACP-DRLF pep-lab
standard
No
A 21-aa standard natural anticancer peptide sequence curated from ACP740 _ACP240, AntiCP 2.0, CancerPPD 2.0, and other sources, with an available 3D structural model.
Sequence
GIIKKIIIKKIIIKKIIIKKI
Physicochemical Analysis
C122H233N29O22
ARNDCEQHLMFPSTWYV
I
2458.37
11.36
8
0
12
+8
4.21
1.067
222.86
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
12
I
0
L
8
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 12 L: 0 K: 8 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
21
C122H233N29O22
2458.37
11.36
+8
4.21
1.067
Free
L
Cyclic
Free
Antimicrobial
AMP
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
IC50 = 4 µM
Anticancer
4 µM

Target

Pancreatic Cancer
HeLa
Pancreatic

Assay & Model

WST-1 assay
Not Available

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2011

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
IC50 = 10 µM
Anticancer
10 µM

Target

Pancreatic Cancer
HL-60
Pancreatic

Assay & Model

WST-1 assay
Not Available

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2011