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Peptide record

TPDB41167

MagaininF5W-Arg Anticancer standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB41167
MagaininF5W-Arg
Anticancer
Cancer-related peptides
CancerPPD 2.0
standard
No
A 23-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
Sequence
GIGRWLHSARRFGRAFVGEIMNS
Physicochemical Analysis
C116H181N39O29S1
DCQKPTY
RG
2618.02
12.40
5
1
10
+3
1.15
-0.183
72.17
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
210.08
3
Residue Composition
number
2
A
4
R
1
N
0
D
0
C
1
E
0
Q
4
G
1
H
2
I
1
L
0
K
1
M
2
F
0
P
2
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 4 N: 1 D: 0 C: 0 E: 1 Q: 0 G: 4 H: 1 I: 2 L: 1 K: 0 M: 1 F: 2 P: 0 S: 2 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
23
C116H181N39O29S1
2618.02
12.40
+3
1.15
-0.183
Free
L
Linear
Free
Antimicrobial
Synthetic
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
IC50 = 16.8 µM
Anticancer
16.8 µM

Target

Blood Cancer
Jurkat
Blood

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2020

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.